New Nutrition and Exercise Guidelines for Cancer Survivors

The American Cancer Society provides nutrition and physical activity guidelines for cancer survivors during phases of treatment and recovery and for others living with advanced cancer. (CME,CE)
Medscape Medical News

Highlights From MMWR: Prescription Drug Use Linked to Fatal Crashes and More

The CDC has reported on alcohol and drug use among victims of motor vehicle crashes; environmental barriers to healthcare among disabled individuals; and prostate-specific antigen levels in men aged 40 years and older.
Medscape Medical News
Yael Waknine

FDA Orphan Drug Approvals: VariZIG, Pafuramidine Maleate, RG1068

The FDA has granted orphan drug status for varicella zoster immune globulin [human] injection, pafuramidine maleate, and synthetic human secretin.
Medscape Medical News
Yael Waknine

Trandolapril-Verapamil May Reduce Risk for Diabetes

A randomized trial showed that in patients with impaired fasting glucose tolerance, this fixed-dose combination reduced the risk for new-onset diabetes vs losartan-hydrochlorothiazide. (CME)
Medscape Medical News
Laurie Barclay,Charles Vega

NEAD: In Utero Exposure To Valproate Linked to Poor Cognitive Outcomes in Kids

In utero exposure to the antiepileptic drug valproate poses a much greater risk of poor behavioral developmental outcomes compared with other commonly used antiepileptic drugs, a new study suggests.
Medscape Medical News
Caroline Cassels

Third Case of vCJD After Blood Transfusion Reported in United Kingdom

A report this week describes a third autopsy-confirmed case of variant Creutzfeldt-Jakob disease infection in a group of patients who received blood from infected donors. The case adds weight to the possibility that the disease-causing prion may be transmitted efficiently by blood transfusions
Medscape Medical News
Susan Jeffrey

Antidepressants Linked With Attempted Suicide Risk in Certain Patients

Antidepressants were linked with increased risk for attempted suicide but improved mortality rates among patients with a history of attempted suicide. (CME,CE)
Medscape Medical News

FDA Approvals: Tyzeka and Humira

The FDA has approved telbivudine 600-mg tablets (Tyzeka) and an expanded indication for adalimumab subcutaneous injection (Humira). (CME)
Medscape Medical News
Laurie Barclay,Yael Waknine

Literature Review Reveals CKD Population With CVD Is Undertreated

A literature review of recent articles about cardiovascular complications in CKD found great research interest but also identified how care could be improved.
Medscape Medical News
Marlene Busko

Experimental Agent Shows Promise as Safe, Effective Antiepileptic

An experimental agent is showing promise as an effective and safe replacement for the ketogenic diet and may pave the way for a new class of drugs to treat temporal lobe epilepsy, a new study suggests.
Medscape Medical News
Caroline Cassels

Stem-Cell Transplant Patients Face Long-Term Cancer Risk

A new study reveals that within 10 years of a hematopoietic stem-cell transplant, patients are almost twice as likely as the general population to develop a second solid cancer.
Medscape Medical News
Allison Gandey

Fortified Milk Helps Prevent Diarrhea and Pneumonia in Preschool Children

In an Indian study, consumption of milk fortified with specific micronutrients significantly reduced illnesses, especially in the first 2 years of life. (CME)
Medscape Medical News
Laurie Barclay,Penny Murata

FDA Safety Changes: Videx, Videx EC, Seroquel, Suprane

The FDA has approved revisions to the safety labeling for didanosine, quetiapine fumarate, and desflurane. (CME)
Medscape Medical News
Laurie Barclay,Yael Waknine

Stopping Clopidogrel Therapy Increases Mortality in Patients With Drug-Eluting Stents

An observational study found that patients treated with drug-eluting stents who are no longer taking clopidogrel at 6 or 12 months face a higher risk for death or MI during 24 months of follow-up. (CME,CE)
Medscape Medical News
Charles Vega,Shelley Wood

Five-Year Data on Imatinib Show Best-Ever Survival With Chronic Myeloid Leukemia

The 5-year overall survival of 89% with imatinib in chronic myeloid leukemia is the best ever reported for this disease.
Medscape Medical News
Zosia Chustecka

Rosiglitazone Delays Treatment Failure in Patients with Type 2 Diabetes

Rosiglitazone is better than metformin and glyburide in slowing the progression to monotherapy failure, although costs, adverse effects, and risk-benefit profile must be taken into account. (CME)
Medscape Medical News
Charles Vega,Michael O'Riordan

Gene Profiling Less Effective in Predicting Lung Cancer

Researchers say the new technique fails to outperform standard histologic examinations, which are less expensive and easily conducted
Medscape Medical News
Allison Gandey

Obesity Had Negative Impact on Renal Transplant Outcomes in Dutch Study

A large retrospective analysis of data from the Netherlands found lower graft and patient survival in obese vs nonobese renal transplant recipients.
Medscape Medical News
Marlene Busko

Low-Fat Diet in Infancy May Improve Endothelial Function in 11-Year-Old Boys

A randomized study suggested that a low-fat diet in 7-month-old infants is associated with improved endothelial function at age 11 years for boys, but not girls, perhaps by reducing cholesterol. (CME)
Medscape Medical News
Laurie Barclay,Gary Vogin

Combined Scan for Accurate Tumor Staging in Colorectal Cancer

A preliminary study suggests that a whole-body scan with combination PET-CT for tumor staging in colorectal cancer saves time and is easier for both patients and doctors.
Medscape Medical News
Zosia Chustecka

Teen Boys Have Higher Risk for Elevated BP Than Teen Girls

Boys are more likely to develop high systolic blood pressure during their teen years vs girls; there was a 19% annual increase in systolic blood pressure of boys from age 13 to 17 years. (CME,CE)
Medscape Medical News
Lisa Nainggolan

Primiparous Mothers, but Not Fathers, at Risk for Postpartum Mental Disorders

A cohort study showed that primiparous mothers, but not fathers, had postpartum depression, schizophrenia, and other mental disorders during the first several months after childbirth. (CME)
Medscape Medical News
Laurie Barclay,Hien Nghiem

Coxibs May Have Less Risk for Upper GI Bleeding Than Nonselective NSAIDs or Aspirin

A case-controlled study also suggests that when combined with low-dose aspirin, the differences between nonselective NSAIDs and coxibs tend to disappear. (CME)
Medscape Medical News
Laurie Barclay

Mandatory Generic Substitution of Antiepileptic Drugs Raises Concerns

Mandatory generic substitution of antiepileptic drugs is raising concerns among physicians and patients that this increasingly common practice is causing a rise in breakthrough seizures and subsequent adverse effects, 2 new studies suggest.
Medscape Medical News
Caroline Cassels

International Approvals: Solaraze, Nasonex, Advate

Australia has approved diclofenac sodium 3% gel (Solaraze), Canada has approved a new indication for mometasone furoate monohydrate nasal spray (Nasonex), and Japan has approved rurioctocog alfa [recombinant, plasma-albumin-free method: rAHF-PFM] infusion (Advate).
Medscape Medical News
Yael Waknine

FDA Approvals: Macroplastique, I-Stop TOMS, and Nidek EC-5000

The FDA has approved a urethral bulking agent (Macroplastique), a propylene mesh urethral sling (I-Stop TOMS), and a new indication for an excimer laser system (Nidek EC-5000).
Medscape Medical News
Yael Waknine

TV Viewing Has Analgesic Effect During Venipuncture in Children

A study showed that children who were distracted by television rather than by their mothers during venipuncture reported less pain. (CME)
Medscape Medical News

Self-Management Helpful in Men With Lower Urinary Tract Symptoms

In men with lower urinary tract symptoms, a self-management intervention reduced symptoms as well as the frequency of treatment failure. (CME)
Medscape Medical News
Laurie Barclay,Charles Vega

Good Nutrition May Help Prevent Disability in the Elderly

A longitudinal study suggests that low serum concentrations of vitamins B6 and B12 and selenium predict subsequent disability in activities of daily living in community-dwelling older women. (CME,CE)
Medscape Medical News
Laurie Barclay,Charles Vega

Acute Hypothalamic Stimulation Not Effective for Ongoing Cluster Headache

Although long-term hypothalamic stimulation is effective in improving drug-resistant cluster headache, researchers report that stimulation did not effectively resolve acute attacks.
Medscape Medical News
Susan Jeffrey

Treating Sleep Apnea May Reduce Seizure Frequency in Refractory Epilepsy

Treating obstructive sleep apnea may significantly reduce seizure frequency in patients with refractory epilepsy, a new pilot study suggests.
Medscape Medical News
Caroline Cassels

KidniCare Model Proposed to Improve Medicare's ESRD Payment System

The need to revamp the current ESRD payment system was discussed and a new program, KidniCare, was proposed in a lecture at the ASN meeting.
Medscape Medical News
Marlene Busko

Deadlock Resolved Between Detroit Medical Center and Wayne State University

The new multiple-year contract, announced November 22 by Governor Jennifer Granholm, hopes to overcome former disputes and ensure long-term stability in the partnership.
Medscape Medical News
Laurie Barclay